Hydrochloric Acid → 5-chloro-6-(2,4,6-trifluorophenyl)-N-(1,1,1-trifluoropropan-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

HRID 115967

Reaction equation

HRID 115967 reaction equation
[CH3:38][N:39]([CH3:40])[CH:41]=[O:42].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[CH:29]([N:30]([CH2:31][CH3:32])[CH:33]([CH3:34])[CH3:35])([CH3:36])[CH3:37].[Cl:1][c:2]1[n:3][c:4]2[n:5]([c:6]([Cl:17])[c:7]1-[c:8]1[c:9]([F:16])[cH:10][c:11]([F:15])[cH:12][c:13]1[F:14])[n:18][cH:19][n:20]2.[ClH:21].[F:22][C:23]([CH:24]([CH3:25])[NH2:26])([F:27])[F:28]>>[Cl:1][c:2]1[n:3][c:4]2[n:5]([c:6]([NH:26][CH:24]([C:23]([F:22])([F:27])[F:28])[CH3:25])[c:7]1-[c:8]1[c:9]([F:16])[cH:10][c:11]([F:15])[cH:12][c:13]1[F:14])[n:18][cH:19][n:20]2

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 81531DiisopropylethylamineHCID 37831651,1,1-Trifluoro-2-propanamineHCID 110453875,7-Dichloro-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidine

Product 1

HCID 98436575-chloro-6-(2,4,6-trifluorophenyl)-N-(1,1,1-trifluoropropan-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Sources & evidence

ORD record
ord-833da28719b145588087a3a3f68cf70d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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