[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][C:3]=1[O:10][CH3:11].[I-].[Na+].C(=O)([O-])[O-].[K+].[K+].Br[CH2:21][C:22]([C:24]1[CH:29]=[C:28]([CH:30]2[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]2)[C:27]([OH:36])=[C:26]([CH:37]2[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]2)[CH:25]=1)=[O:23].Cl>C(OCC)(=O)C>[CH:30]1([C:28]2[CH:29]=[C:24]([C:22](=[O:23])[CH2:21][O:1][C:2]3[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][C:3]=3[O:10][CH3:11])[CH:25]=[C:26]([CH:37]3[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]3)[C:27]=2[OH:36])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]1A mixture of 1.52 g (10 mmol) of 4-hydroxy-3-methoxy-benzaldehyde, 0.3 g (2.0 mmol) of sodium iodide and 3.05 g (22 mmol) of potassium carbonate in 80 ml of ethyl acetate is stirred for 30 minutes. Then 3.8 g (10 mmol) of 2-bromo-1-(4-hydroxy-3,5-di-cyclohexylphenyl)-ethanone is added and stirring at room temperature is continued for 16 hours. Then the mixture is acidified with 2N HCl and extracted with ethyl acetate. The combined extracts are washed with water, dried and evaporated. Crystallization of the crude product from dichloro-methane/di-isopropylether yields 1.35 g of compound 103, m.p. 163-164° C.
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