Sodium ion → [2-(5-Phenylethynyl-thiophen-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine

HRID 118989

Reaction equation

HRID 118989 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:7]2[n:8][c:9]3[n:10]([cH:11][cH:12][cH:13][cH:14]3)[c:15]2[NH:16][C:17]([CH2:18][C:19]([CH3:20])([CH3:21])[CH3:22])([CH3:23])[CH3:24])[s:6]1.[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[Cu:92][I:93].[Na+:40].[Na+:41].[O-:42][C:43](=[O:44])[O-:45].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50].[Pd:51]([Cl:52])[Cl:53].[c:25]1([C:31]#[CH:32])[cH:26][cH:27][cH:28][cH:29][cH:30]1.[c:54]1([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1.[c:73]1([P:74]([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[cH:87][cH:88][cH:89][cH:90][cH:91]1>>[c:2]1([C:32]#[C:31][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[cH:3][cH:4][c:5](-[c:7]2[n:8][c:9]3[n:10]([cH:11][cH:12][cH:13][cH:14]3)[c:15]2[NH:16][C:17]([CH2:18][C:19]([CH3:20])([CH3:21])[CH3:22])([CH3:23])[CH3:24])[s:6]1

Participants

10

Reactant 9

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 8471TriethylamineHCID 10821PhenylacetyleneHCID 11776Triphenylphosphine2×HCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 69317913[2-(5-Bromothiophen-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine

Product 1

HCID 11604327[2-(5-Phenylethynyl-thiophen-2-yl)-imidazo[1,2-a]pyridin-3-yl]-(1,1,3,3-tetramethyl-butyl)-amine

Sources & evidence

ORD record
ord-d73a7cfc09f74bda9a4c0c5103690c9f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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