Tetrahydrofuran → 5-Fluoro-3-((trimethylsilyl)ethynyl)pyridin-2-amine
Reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:10][Si:11]([CH3:12])([CH3:13])[C:14]#[CH:15].[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[Cu:28][I:29].[F:1][c:2]1[cH:3][c:4]([I:9])[c:5]([NH2:8])[n:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4]([C:15]#[C:14][Si:11]([CH3:10])([CH3:12])[CH3:13])[c:5]([NH2:8])[n:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-3bedb231b0534c44927a478e0354162c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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