Hydrochloric Acid → Methyl 4-(cyclohexyloxy)-2-(4-fluoroanilino)benzoate

HRID 134596

Reaction equation

HRID 134596 reaction equation
[C:20](=[O:21])([O-:22])[O-:23].[CH3:34][CH2:35][O:36][C:37](=[O:38])[CH3:39].[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[CH:26]1([Br:32])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]1.[ClH:33].[F:1][c:2]1[cH:3][cH:4][c:5]([NH:6][c:7]2[c:8]([C:9](=[O:10])[O:11][CH3:12])[cH:13][cH:14][c:15]([OH:17])[cH:16]2)[cH:18][cH:19]1.[K+:24].[K+:25]>>[F:1][c:2]1[cH:3][cH:4][c:5]([NH:6][c:7]2[c:8]([C:9](=[O:10])[O:11][CH3:12])[cH:13][cH:14][c:15]([O:17][CH:26]3[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]3)[cH:16]2)[cH:18][cH:19]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 7960Cyclohexyl bromideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 57667875Methyl 2-(4-fluoroanilino)-4-hydroxybenzoate

Product 1

HCID 57668066Methyl 4-(cyclohexyloxy)-2-(4-fluoroanilino)benzoate

Sources & evidence

ORD record
ord-8d74bc5851fd4053a1910a34a3032485
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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