Dimethylformamide → Benzyl 4-benzyl-3-oxopiperazine-1-carboxylate

HRID 137020

Reaction equation

HRID 137020 reaction equation
[Br:33][CH2:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:18][Si:19]([N-:20][Si:21]([CH3:22])([CH3:23])[CH3:24])([CH3:25])[CH3:26].[Li+:27].[O:1]=[C:2]1[CH2:3][N:4]([C:8](=[O:9])[O:10][CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[CH2:5][CH2:6][NH:7]1.[O:41]=[CH:42][N:43]([CH3:44])[CH3:45]>>[O:1]=[C:2]1[CH2:3][N:4]([C:8](=[O:9])[O:10][CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[CH2:5][CH2:6][N:7]1[CH2:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 736777Benzyl 3-oxopiperazine-1-carboxylateHCID 3280088Npc316347

Product 1

HCID 59750509Benzyl 4-benzyl-3-oxopiperazine-1-carboxylate

Sources & evidence

ORD record
ord-3c465f66acca4defa738160347a2b0d2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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