1,2-Dichloroethane → 2-(3-fluoro-4-phenylphenyl)-N-[1-(5-methoxy-2-pyridinyl)ethyl]propanamide

HRID 153611

Reaction equation

HRID 153611 reaction equation
[CH2:31]([Cl:32])[CH2:33][Cl:34].[CH3:20][O:21][c:22]1[cH:23][cH:24][c:25]([CH:28]([CH3:29])[NH3+:30])[n:26][cH:27]1.[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[Cl-:19].[Cl:49][CH2:50][Cl:51].[F:1][c:2]1[c:3](-[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:4][cH:5][c:6]([CH:8]([C:9](=[O:10])[OH:11])[CH3:12])[cH:7]1.[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[F:1][c:2]1[c:3](-[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:4][cH:5][c:6]([CH:8]([C:9](=[O:11])[NH:30][CH:28]([c:25]2[cH:24][cH:23][c:22]([O:21][CH3:20])[cH:27][n:26]2)[CH3:29])[CH3:12])[cH:7]1

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 312ChlorideHCID 3394FlurbiprofenHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 178490387HCID 178490387, compound

Product 1

HCID 1745883832-(3-fluoro-4-phenylphenyl)-N-[1-(5-methoxy-2-pyridinyl)ethyl]propanamide

Sources & evidence

ORD record
ord-660c20eabf4f41f4ace87046846db61f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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