Dimethylformamide → (4-nitrophenyl)methyl 3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-6-[2-[(4-nitrophenyl)methoxycarbonyloxy]propan-2-yl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

HRID 158160

Reaction equation

HRID 158160 reaction equation
[CH2:80]([Cl:81])[Cl:82].[CH3:64][c:65]1[n:66][n:67][c:68]([SH:70])[s:69]1.[CH3:71][N:72]([c:73]1[cH:74][cH:75][n:76][cH:77][cH:78]1)[CH3:79].[CH3:83][N:84]([CH3:85])[CH:86]=[O:87].[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[F:49][C:50]([S:51]([O:52][S:53]([C:54]([F:55])([F:56])[F:57])(=[O:58])=[O:59])(=[O:60])=[O:61])([F:62])[F:63].[O:10]=[C:11]1[CH:12]([C:36](=[O:37])[O:38][CH2:39][c:40]2[cH:41][cH:42][c:43]([N+:46](=[O:47])[O-:48])[cH:44][cH:45]2)[N:13]2[C:14](=[O:35])[CH:15]([C:18]([CH3:19])([O:20][C:21](=[O:22])[O:23][CH2:24][c:25]3[cH:26][cH:27][c:28]([N+:31](=[O:32])[O-:33])[cH:29][cH:30]3)[CH3:34])[CH:16]2[CH2:17]1>>[C:11]1([S:70][c:68]2[n:67][n:66][c:65]([CH3:64])[s:69]2)=[C:12]([C:36](=[O:37])[O:38][CH2:39][c:40]2[cH:41][cH:42][c:43]([N+:46](=[O:47])[O-:48])[cH:44][cH:45]2)[N:13]2[C:14](=[O:35])[CH:15]([C:18]([CH3:19])([O:20][C:21](=[O:22])[O:23][CH2:24][c:25]3[cH:26][cH:27][c:28]([N+:31](=[O:32])[O-:33])[cH:29][cH:30]3)[CH3:34])[CH:16]2[CH2:17]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 67749Trifluoromethanesulfonic anhydrideHCID 81531DiisopropylethylamineHCID 178434161HCID 178434161, compoundHCID 178459901HCID 178459901, compound

Product 1

HCID 178434144(4-nitrophenyl)methyl 3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-6-[2-[(4-nitrophenyl)methoxycarbonyloxy]propan-2-yl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

Sources & evidence

ORD record
ord-ee897d414af34e19b4970914bbf780a9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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