Ammonium → tert-butyl 4-{2-[methoxy(methyl)amino]-2-oxo-1-(tetrahydro-2H-pyran-4-ylmethyl)ethyl}benzoate

HRID 200173

Reaction equation

HRID 200173 reaction equation
[CH3:44][N:45]1[CH2:46][CH2:47][CH2:48][N:49]([CH3:50])[C:51]1=[O:52].[CH3:9][O:10][N:11]([C:12]([CH2:13][c:14]1[cH:15][cH:16][c:17]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26]1)=[O:27])[CH3:28].[CH:1]([N-:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl-:37].[I:29][CH2:30][CH:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1.[Li+:8].[NH4+:38].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH3:9][O:10][N:11]([C:12]([CH:13]([c:14]1[cH:15][cH:16][c:17]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26]1)[CH2:30][CH:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1)=[O:27])[CH3:28]

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 816462(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-HCID 27955074-(Iodomethyl)oxaneHCID 5062348DiisopropylamideHCID 59331582Tert-butyl 4-{2-[methoxy(methyl)amino]-2-oxoethyl}benzoate

Product 1

HCID 59331574tert-butyl 4-{2-[methoxy(methyl)amino]-2-oxo-1-(tetrahydro-2H-pyran-4-ylmethyl)ethyl}benzoate

Sources & evidence

ORD record
ord-e626ba849fec43ad93a6ca63407ee93d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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