Hydrochloric Acid → 2-Propenoic acid, 3-phenyl-

HRID 22097

Reaction equation

HRID 22097 reaction equation
[C:1]([O:14]C)(=[O:13])/[CH:2]=[CH:3]/[C:4]1[CH:12]=[CH:11][C:8](OC)=[C:6](O)[CH:5]=1.[H-].[Na+].C1OC1CO.Cl>CS(C)=O>[C:1]([OH:14])(=[O:13])[CH:2]=[CH:3][C:4]1[CH:5]=[CH:6][CH:8]=[CH:11][CH:12]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 11164GlycidolHCID 24758Sodium hydrideHCID 6439893Methyl isoferulate

Product 1

HCID 87842-Propenoic acid, 3-phenyl-

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

3 g of methyl isoferulate was dissolved in 600 ml of DMSO, and 370 mg of sodium hydride was added. The system was heated to 90° C. under N2 gas flow and 7 g of glycidol was added gradually. Heating and agitation was carried out for 0.5 hours. The system was cooled, neutralized by adding hydrochloric acid, solvent was removed and adduct of cinnamic acid and glycerin was obtained.

Workup

  1. additionwas added gradually
  2. temperatureHeating
  3. temperatureThe system was cooled
  4. customwas removed

Sources & evidence

ORD record
ord-f297ae3acb9542e7bf85a53dda6a37d2
Source dataset
uspto-grants-1995_06
Patent number
US05426210

Linked notes

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