Hydrochloric Acid → 1-cyclopropyl-N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide

HRID 2335346

Reaction equation

HRID 2335346 reaction equation
[CH3:2][N:3]([CH3:4])[CH2:5][CH2:6][CH2:7][N:8]=[C:9]=[N:10][CH2:11][CH3:12].[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[CH3:47][N:48]([CH3:49])[c:50]1[cH:51][cH:52][n:53][cH:54][cH:55]1.[CH:30]1([N:33]2[CH2:34][CH2:35][CH:36]([C:39](=[O:40])[OH:41])[CH2:37][CH2:38]2)[CH2:31][CH2:32]1.[Cl:57][CH2:58][Cl:59].[ClH:1].[NH2:13][c:14]1[s:15][c:16]([S:19][CH2:20][c:21]2[o:22][c:23]([C:26]([CH3:27])([CH3:28])[CH3:29])[cH:24][n:25]2)[cH:17][n:18]1.[OH2:56]>>[NH:13]([c:14]1[s:15][c:16]([S:19][CH2:20][c:21]2[o:22][c:23]([C:26]([CH3:27])([CH3:28])[CH3:29])[cH:24][n:25]2)[cH:17][n:18]1)[C:39]([CH:36]1[CH2:35][CH2:34][N:33]([CH:30]2[CH2:31][CH2:32]2)[CH2:38][CH2:37]1)=[O:40]

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 110654845-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-amineHCID 162440131-CYCLOPROPylpiPERIDINE-4-CARBOXYLIC ACID

Product 1

HCID 102023351-cyclopropyl-N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide

Sources & evidence

ORD record
ord-1b4859bd4825480688c1ee7f6bfdf831
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Linked notes

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