Toluene → Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

HRID 286169

Reaction equation

HRID 286169 reaction equation
[CH2:2]([Cl:3])[C:4]#[CH:5].[CH3:20][CH2:21][O:22][C:23](=[O:24])[CH3:25].[CH3:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1.[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[NH2:6][c:7]1[s:8][cH:9][c:10]([C:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])=[N:18][OH:19])[n:11]1.[Na:1]>>[NH2:6][c:7]1[s:8][cH:9][c:10]([C:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])=[O:22])[n:11]1

Participants

7

Reactant 6

HCID 1140TolueneHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 122213-Chloro-1-propyneHCID 5360545SodiumHCID 6738988Ethyl 2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetate

Product 1

HCID 4356513Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

Sources & evidence

ORD record
ord-5721391abc4d469f913bf491988a39a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…