Dimethylformamide → 5-bromo-N-[4-chloro-5-({7-cyano-2-[(cyclopropylcarbonyl)amino]-1,3-benzothiazol-6-yl}oxy)-2-fluorophenyl]-1-methyl-1H-pyrazole-4-carboxamide
Reaction equation
[Br:1][c:2]1[c:3]([C:8](=[O:9])[OH:10])[cH:4][n:5][n:6]1[CH3:7].[CH3:17][N:18]([CH3:19])[CH:20]=[O:21].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[Cl:11][C:12]([C:13]([Cl:14])=[O:15])=[O:16].[NH2:22][c:23]1[c:24]([F:48])[cH:25][c:26]([Cl:47])[c:27]([O:28][c:29]2[c:30]([C:44]#[N:45])[c:31]3[c:32]([n:33][c:34]([NH:36][C:37](=[O:38])[CH:39]4[CH2:40][CH2:41]4)[s:35]3)[cH:42][cH:43]2)[cH:46]1.[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1>>[Br:1][c:2]1[c:3]([C:8](=[O:10])[NH:22][c:23]2[c:24]([F:48])[cH:25][c:26]([Cl:47])[c:27]([O:28][c:29]3[c:30]([C:44]#[N:45])[c:31]4[c:32]([n:33][c:34]([NH:36][C:37](=[O:38])[CH:39]5[CH2:40][CH2:41]5)[s:35]4)[cH:42][cH:43]3)[cH:46]2)[cH:4][n:5][n:6]1[CH3:7]
