Water → (4-chlorophenyl)methyl 4-[4-[(2-methyl-6-nitro-3H-imidazo[2,1-b][1,3]oxazol-2-yl)methoxy]phenyl]piperazine-1-carboxylate

HRID 304948

Reaction equation

HRID 304948 reaction equation
[C:50]([n:51]1[cH:52][cH:53][n:54][cH:55]1)([n:56]1[cH:57][cH:58][n:59][cH:60]1)=[O:61].[CH2:62]([Cl:63])[Cl:64].[CH3:1][C:2]1([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18]([N:21]3[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][C:30]([CH3:31])([CH3:32])[CH3:33])[CH2:25][CH2:26]3)[cH:19][cH:20]2)[CH2:3][n:4]2[c:5]([n:7][c:8]([N+:10](=[O:11])[O-:12])[cH:9]2)[O:6]1.[Cl:41][c:42]1[cH:43][cH:44][c:45]([CH2:46][OH:47])[cH:48][cH:49]1.[O:65]=[CH:66][N:67]([CH3:68])[CH3:69].[OH2:70].[OH:34][C:35]([C:36]([F:37])([F:38])[F:39])=[O:40]>>[CH3:1][C:2]1([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18]([N:21]3[CH2:22][CH2:23][N:24]([C:27](=[O:28])[O:29][CH2:46][c:45]4[cH:44][cH:43][c:42]([Cl:41])[cH:49][cH:48]4)[CH2:25][CH2:26]3)[cH:19][cH:20]2)[CH2:3][n:4]2[c:5]([n:7][c:8]([N+:10](=[O:11])[O-:12])[cH:9]2)[O:6]1

Participants

8

Reactant 7

HCID 962WaterHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 133974-Chlorobenzyl alcoholHCID 682631,1'-CarbonyldiimidazoleHCID 23081090Tert-butyl 4-[4-(2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazol-2-ylmethoxy)phenyl]piperazine-1-carboxylate

Product 1

HCID 77712921(4-chlorophenyl)methyl 4-[4-[(2-methyl-6-nitro-3H-imidazo[2,1-b][1,3]oxazol-2-yl)methoxy]phenyl]piperazine-1-carboxylate

Sources & evidence

ORD record
ord-9c94d07e5dc14a30acc4aff5ea79b212
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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