Methyl Chloride → CHCl2CF2CHFCF3

Reaction equation

C[Cl:2].CF.C(F)F.[CH:8]([Cl:11])(F)F.[F:12][C:13]([F:20])([F:19])[C:14]([F:18])=[C:15]([F:17])[F:16].FF>C(Cl)Cl.C(Cl)(Cl)(Cl)Cl.C(Cl)(Cl)Cl>[CH:8]([C:15]([CH:14]([C:13]([F:20])([F:19])[F:12])[F:18])([F:17])[F:16])([Cl:11])[Cl:2]

Participants

Reactant 6

HCID 6327Methyl Chloride

HCID 6345Difluoromethane

HCID 6372Chlorodifluoromethane

HCID 8302Hexafluoropropylene2×

HCID 11638Fluoromethane

HCID 24524Fluorine

Product 1

HCID 12829383CHCl2CF2CHFCF3Yield 85%

Reagents, catalysts & solvents

Procedure

Typical compounds conforming to the above general formula are CH3Cl, CH2Cl2, CHCl3, CCl4, CH3F, CH2F2, CHF2Cl, and the like. Addition of such compounds to hexafluoropropene thermally is described in J. Fluorine Chemistry 1982, 21, 253-259. For example, CH2Cl2 addition to CF3CF═CF2 at 280° C. is reported to give 85% yield of CHCl2CF2CHFCF3.