Piperidine → 5-(p-Cyanophenyl)-4-pentynoic acid

HRID 686757

Reaction equation

[Br:8][c:9]1[cH:10][cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]1.[C:1]([CH2:2][CH2:3][C:4]#[CH:5])(=[O:6])[OH:7].[CH2:17]1[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]1.[CH3:23][CH2:24][O:25][C:26](=[O:27])[CH3:28]>>[C:1]([CH2:2][CH2:3][C:4]#[C:5][c:9]1[cH:10][cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]1)(=[O:6])[OH:7]

Participants

Reactant 4

HCID 8082Piperidine

HCID 8857Ethyl Acetate

HCID 12162Benzonitrile, 4-bromo-

HCID 224644-Pentynoic acid

Product 1

HCID 189975535-(p-Cyanophenyl)-4-pentynoic acid

Sources & evidence

ORD record: ord-14c782e1f3474e1c86c33e397013019b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Linked notes

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