1-Amino-2-propanol → 4-(2-fluoro-4-iodoanilino)-N-(2-hydroxypropyl)-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamide
Reaction equation
[C:21]([n:22]1[cH:23][cH:24][n:25][cH:26]1)([n:27]1[cH:28][cH:29][n:30][cH:31]1)=[O:32].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:38][CH2:39][CH2:40][CH2:41][CH2:42][CH3:43].[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:14])[OH:15])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:16][cH:17][c:18]([I:20])[cH:19]1.[NH2:33][CH2:34][CH:35]([CH3:36])[OH:37].[O:49]=[CH:50][N:51]([CH3:52])[CH3:53]>>[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:15])[NH:33][CH2:34][CH:35]([CH3:36])[OH:37])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:16][cH:17][c:18]([I:20])[cH:19]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-ffe76bfd22b04053a52e9c21cf4cfd62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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