Triethylamine → 2-(Cyclopropylethynyl)-4-nitroaniline

HRID 820344

Reaction equation

HRID 820344 reaction equation
[Br:1][c:2]1[c:3]([NH2:4])[cH:5][cH:6][c:7]([N+:9](=[O:10])[O-:11])[cH:8]1.[C:12](#[CH:13])[CH:14]1[CH2:15][CH2:16]1.[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[Cu:24][I:25].[Pd:26]([Cl:27])[Cl:28].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[c:2]1([C:13]#[C:12][CH:14]2[CH2:15][CH2:16]2)[c:3]([NH2:4])[cH:5][cH:6][c:7]([N+:9](=[O:10])[O-:11])[cH:8]1

Participants

7

Reactant 6

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 25840Benzenamine, 2-bromo-4-nitro-HCID 138823Cyclopropylacetylene

Product 1

HCID 591292622-(Cyclopropylethynyl)-4-nitroaniline

Sources & evidence

ORD record
ord-31b9e6136bca499dbba2023d6700c25d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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