Dimethylformamide → 3-tert-butoxycarbonyl-7-chloro-6-(3-methoxycarbonyl-propyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][C:5](=[O:6])[O:7][CH3:8].[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH2:17][CH2:18][c:19]2[c:20]([c:23]([OH:28])[c:24]([Cl:27])[cH:25][cH:26]2)[CH2:21][CH2:22]1.[CH2:29]1[CH2:30][CH2:31][C:32]2=[N:37][CH2:36][CH2:35][CH2:34][N:33]2[CH2:38][CH2:39]1.[CH3:45][CH2:46][CH2:47][CH2:48][CH2:49][CH3:50].[CH3:51][CH2:52][O:53][C:54]([CH3:55])=[O:56].[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[CH2:2]([CH2:3][CH2:4][C:5](=[O:6])[O:7][CH3:8])[O:28][c:23]1[c:20]2[c:19]([cH:26][cH:25][c:24]1[Cl:27])[CH2:18][CH2:17][N:16]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:15])[CH2:22][CH2:21]2
