Phenylpyruvic acid → Sodium 2-oxo-3-phenylbutanoate
反応式
[OH-].[Na+:2].[C:3]1([CH2:9][C:10](=[O:14])[C:11]([OH:13])=[O:12])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:15]I>O1CCCC1>[O:14]=[C:10]([CH:9]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[CH3:15])[C:11]([O-:13])=[O:12].[Na+:2]参加物
5
実験手順
A 1N aqueous solution of sodium hydroxide (20 ml, 20 mmoles) and 30 ml of tetrahydrofuran were added to 1.64 g (10.0 mmoles) of phenylpyruvic acid to form a solution. Then, 2.0 ml of methyl iodide was added, and the mixture was stirred at room temperature for 10 hours. The reaction mixture was concentrated, and ether was added to the resulting pale yellowish white semi-solid. The precipitated sodium 2-oxo-3-phenylbutanoate as a white solid (0.68 g, yield 68 %) was isolated by filtration.
後処理
- customto form a solution
- concentrationThe reaction mixture was concentrated
- additionether was added to the resulting pale yellowish white semi-solid
出典と根拠
- ORDレコード
- ord-e00b7c8585e447fbb58d58e56489a553
- 出典データセット
- uspto-grants-1991_07
- 特許番号
- US05028738
反応ノート
読み込み中…