Ethyl chloroformate → Ethyl 2,2-dimethoxyethylcarbamate
反応式
Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[CH3:7][O:8][CH:9]([O:12][CH3:13])[CH2:10][NH2:11].[OH-].[Na+]>C1(C)C=CC=CC=1.O>[CH3:7][O:8][CH:9]([O:12][CH3:13])[CH2:10][NH:11][C:2](=[O:3])[O:4][CH2:5][CH3:6]参加物
6
実験手順
214 g (2 mol) of ethyl chloroformate are added dropwise to 214 g (2 mol) of aminoacetaldehyde dimethyl acetal in 1 l of toluene and 90 g of NaOH in 500 ml of water at 10° C. The mixture is stirred at room temperature for a further 2 hours and the aqueous phase is separated off, saturated with sodium chloride and extracted with toluene. The toluene solutions are dried over magnesium sulphate and concentrated and the residue is distilled.
後処理
- customthe aqueous phase is separated off, saturated with sodium chloride
- extractionextracted with toluene
- dry with materialThe toluene solutions are dried over magnesium sulphate
- concentrationconcentrated
- distillationthe residue is distilled
出典と根拠
- ORDレコード
- ord-9d97b7ac3ac0435c8feda74e2c76dc3b
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05416096
反応ノート
読み込み中…