2-Aminothiazole → HCID 22335581、化合物

HRID 431229

反応式

HRID 431229 の反応式
[NH2:1][C:2]1[S:3][CH:4]=[CH:5][N:6]=1.[CH:7]1([N+:13]#[C-:14])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1.[CH3:15][C:16]1[CH:23]=[C:22]([CH3:24])[CH:21]=[CH:20][C:17]=1[CH:18]=O>Cl(O)(=O)(=O)=O>[CH:7]1([NH:13][C:14]2[N:6]3[C:2]([S:3][CH:4]=[CH:5]3)=[N:1][C:18]=2[C:17]2[CH:20]=[CH:21][C:22]([CH3:24])=[CH:23][C:16]=2[CH3:15])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1

参加物

5

反応物 3

HCID 21552-AminothiazoleHCID 618142,4-DimethylbenzaldehydeHCID 79129Cyclohexyl isocyanide

生成物 1

HCID 22335581HCID 22335581、化合物

試薬・触媒・溶媒 1

HCID 24247Perchloric Acid溶媒

実験手順

Compound 50 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-amino thiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2,4-dimethylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

出典と根拠

ORDレコード
ord-2e0724f52e6d46bd9d1719219e1b4490
出典データセット
uspto-grants-2003_12
特許番号
US06657064B2

関連ノート

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