Iodoethane → HCID 22736975、化合物

HRID 51874

反応式

HRID 51874 の反応式
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11]C=2C(N)=C[CH:4]=1.C(=O)([O-])[O-].[K+].[K+].ICC.Cl.[CH3:24][C:25]1[CH:26]=[C:27]([CH:31]=[CH:32][N:33]=1)[C:28]([OH:30])=O.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.[CH2:58]([N:60]([CH:64]([CH3:66])C)[CH:61]([CH3:63])[CH3:62])[CH3:59]>CN(C=O)C.C1COCC1>[CH2:64]([N:60]([CH2:58][CH3:59])[C:61]1[C:62]2[S:11][C:10]([NH:12][C:28](=[O:30])[C:27]3[CH:31]=[CH:32][N:33]=[C:25]([CH3:24])[CH:26]=3)=[N:9][C:8]=2[C:3]([O:2][CH3:1])=[CH:4][CH:63]=1)[CH3:66]

参加物

9

反応物 6

HCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 81531DiisopropylethylamineHCID 27628242-methylpyridine-4-carboxylic Acid HydrochlorideHCID 9886157Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 227369774-Methoxy-1,3-benzothiazole-2,7-diamine

生成物 1

HCID 22736975HCID 22736975、化合物

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide溶媒HCID 8028Tetrahydrofuran溶媒

実験手順

From 4-methoxy-benzothiazole-2,7-diamine with potassium carbonate and iodoethane in DMF, then treatment with 2-methyl-isonicotinic acid hydrochloride, HATU and N-ethyldiisopropylamine in THF. ES-MS m/e (%): 371 (M+H+, 100).

出典と根拠

ORDレコード
ord-ee1dbe3c18084e539f008643ff9aea13
出典データセット
uspto-grants-2004_03
特許番号
US06713499B2

関連ノート

読み込み中…