Acetyl chloride → HCID 178418859、化合物

HRID 7529

反応式

HRID 7529 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[CH:8]1([N+:14]#[C-:15])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1.[CH:16]1([CH:22]=O)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1.[C:24]([Cl:27])(=[O:26])[CH3:25]>Cl(O)(=O)(=O)=O>[Cl-:27].[C:24]([N+:1]1[C:22]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)=[C:15]([NH:14][CH:8]2[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]2)[N:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=12)(=[O:26])[CH3:25]

参加物

6

反応物 4

HCID 6367Acetyl chlorideHCID 104392-AminopyridineHCID 16275CyclohexanecarboxaldehydeHCID 79129Cyclohexyl isocyanide

生成物 1

HCID 178418859HCID 178418859、化合物

試薬・触媒・溶媒 1

HCID 24247Perchloric Acid溶媒

実験手順

Example 23 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyridine (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) cyclohexane carbaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

出典と根拠

ORDレコード
ord-d6b7304d14924773a356ec02ce0f21c6
出典データセット
uspto-grants-2006_08
特許番号
US07087607B2

関連ノート

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