Hydrochloric Acid → 2-Aminobenzenesulfonic acid

HRID 1632146

반응식

HRID 1632146 반응식
N[C:2]1[C:11]2[C:6](=CC(S(O)(=O)=O)=CC=2O)[CH:5]=[C:4]([S:17]([OH:20])(=[O:19])=[O:18])[CH:3]=1.[N:21]1C(F)=NC(F)=NC=1F.C(=O)([O-])[O-].[Na+].[Na+].NC1C=CC=C(C)C=1.Cl.N([O-])=O.[Na+]>O>[NH2:21][C:5]1[CH:6]=[CH:11][CH:2]=[CH:3][C:4]=1[S:17]([OH:20])(=[O:19])=[O:18]

참가 물질

8

반응물 6

HCID 313Hydrochloric AcidHCID 7009H acidHCID 7934m-Toluidine2회HCID 10340Sodium CarbonateHCID 12664Cyanuric fluorideHCID 23668193Sodium Nitrite

생성물 1

HCID 69262-Aminobenzenesulfonic acid수율 143.6%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

12.8 g of 1-amino-8-hydroxynaphthalene-3,6-disulphonic acid are dissolved in 200 ml of water at pH 5.8. After cooling the solution to 0°-5°, 3.8 g of cyanuric fluoride are added dropwise in the course of 10 minutes, and during this the pH value of the solution is kept at 4.0-4.5 by adding 20% strength sodium carbonate solution dropwise. The mixture is subsequently stirred for about 15 minutes and 4.3 g of m-toluidine are then added. The pH value is now kept at 5.5-6.0. After the condensation of the difluorotriazinyl component with the m-toluidine has ended, a diazonium salt suspension which has been obtained from 7.0 g of 2-aminobenzenesulphonic acid in 100 ml and 20 ml of concentrated hydrochloric acid with 20 ml of 2N sodium nitrite solution analogously to Example 2, is allowed to run in at 0°-5°.

후처리

  1. temperatureAfter cooling the solution to 0°-5°

출처 및 근거

ORD 기록
ord-b61eb0cf1fae426c990804adef3a29fe
출처 데이터셋
uspto-grants-1984_10
특허 번호
US04474697

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