Hydrochloric Acid → [4-(4-Benzoylphenyl)phenyl](phenyl)methanone

HRID 23836

반응식

HRID 23836 반응식
[C:1]1([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:13](Cl)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[Cl-].[Cl-].[Cl-].[Al+3].Cl>[N+](C1C=CC=CC=1)([O-])=O>[C:13]([C:4]1[CH:5]=[CH:6][C:1]([C:7]2[CH:8]=[CH:9][C:10]([C:13](=[O:20])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:11][CH:12]=2)=[CH:2][CH:3]=1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 7095BiphenylHCID 7412Benzoyl chlorideHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 4671929[4-(4-Benzoylphenyl)phenyl](phenyl)methanone

시약·촉매·용매 1

HCID 7416Nitrobenzene용매

반응 조건

온도
35 °C

실험 절차

The photoinitiator dibenzoyl biphenyl was prepared by placing 200 mL nitrobenzene, 38.5 g (0.25 mole) biphenyl, and 140.6 g (1.00 mole) benzoyl chloride into a 1 liter 3-necked flask equipped with a water condenser. While stirring, 160 g (1.2 mole) aluminum trichloride was added slowly over a period of about 30 minutes. During the reaction, the temperature increased from 30° C. to 55° C. The color changed from yellowish to light brown, then reddish. The flask was kept in a water bath at a temperature of 55° C. to 60° C. for 3 hours while stirring. The reaction mixture was then cooled to 35° C. The reaction mixture was poured into 1.2 L of 8% HCl solution with vigorous stirring. The organic layer was separated and poured into a blender and 500 mL n-hexane was added. The mixture was vigorously stirred for 5 minutes and then filtered. The solid was washed with n-hexane. The thus-produced dibenzoyl biphenyl was dried and recrystalized twice in chloroform.

후처리

  1. customequipped with a water condenser
  2. customDuring the reaction
  3. temperaturethe temperature increased from 30° C. to 55° C
  4. stirringwhile stirring
  5. customThe organic layer was separated
  6. additionpoured into a blender and 500 mL n-hexane
  7. additionwas added
  8. stirringThe mixture was vigorously stirred for 5 minutes
  9. filtrationfiltered
  10. washThe solid was washed with n-hexane
  11. dry with materialThe thus-produced dibenzoyl biphenyl was dried
  12. customrecrystalized twice in chloroform

출처 및 근거

ORD 기록
ord-ac15554799264828811d5492b04508e7
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06852894B2

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