Hydrochloric Acid → HCID 178525248, 화합물
반응식
[NH2:1][CH:2]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-])=O)[CH2:3][C:4]([OH:6])=[O:5].Cl>[OH-].[Na+].O.NN.[Ni]>[NH:13]1[C:8]2[C:7](=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:2]([CH2:3][C:4]([OH:6])=[O:5])=[N:1]1참가 물질
6
반응 조건
- 온도
- 80 °C
실험 절차
3-Amino-3-(2-nitrophenyl) propionic acid (15 g, 71.4 mmol) was dissolved in a mixed solution of 5% sodium hydroxide solution (85 mL) and 85% hydrazine hydrate (5 mL). The reaction was heated to 80° C., and then Raney nickel (2×25 mg) was added carefully. After reacted for half an hour, it was cooled, adjusted to pH≈2 with 6 N hydrochloric acid. A solid precipitated was pumping filtered, dried in vacuum to obtain a yellow solid 6.86 g, at a yield of 54.5%.
후처리
- customAfter reacted for half an hour
- temperatureit was cooled
- customA solid precipitated
- filtrationwas pumping filtered
- customdried in vacuum
출처 및 근거
- ORD 기록
- ord-afa96c0cfc2c4fb8b6b2049654696ede
- 출처 데이터셋
- uspto-grants-2016_01
- 특허 번호
- US09233098B2
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