Hydrochloric Acid → Ethyl 5-[[[2-(dimethylamino)ethyl]amino]carbonyl]thiophen-2-carboxylate

HRID 101642Notes

Reaction equation

HRID 101642 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][cH:8][c:9]([C:11](=[O:12])[OH:13])[s:10]1.[CH2:31]([N:32]=[C:33]=[N:34][CH2:35][CH2:36][CH2:37][N:38]([CH3:39])[CH3:40])[CH3:41].[CH2:58]([Cl:59])[Cl:60].[CH3:14][N:15]([CH2:16][CH2:17][NH2:18])[CH3:19].[CH3:51][CH2:52][N:53]([CH2:54][CH3:55])[CH2:56][CH3:57].[CH:47]([Cl:48])([Cl:49])[Cl:50].[ClH:30].[Na+:42].[OH:20][n:21]1[c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]2[n:28][n:29]1.[OH:43][C:44](=[O:45])[O-:46]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][cH:8][c:9]([C:11](=[O:13])[NH:18][CH2:17][CH2:16][N:15]([CH3:14])[CH3:19])[s:10]1

Participants

11

Reactant 10

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 6212ChloroformHCID 6344DichloromethaneHCID 8471TriethylamineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 66053N,N-DimethylethylenediamineHCID 757711-HydroxybenzotriazoleHCID 152321235-(Ethoxycarbonyl)thiophene-2-carboxylic acid

Product 1

HCID 69300800Ethyl 5-[[[2-(dimethylamino)ethyl]amino]carbonyl]thiophen-2-carboxylate

Sources & evidence

ORD record
ord-8cc4a9afcbcd47529f944d759d33a8b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…