Dibromodifluoromethane → HCID 13315035, compound

HRID 1030331Notes

Reaction equation

HRID 1030331 reaction equation
[Na].[OH:2][C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][CH:4]=1.[Br:11][C:12](Br)([F:14])[F:13]>CN(C)C=O>[Br:11][C:12]([F:14])([F:13])[O:2][C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 6382DibromodifluoromethaneHCID 130194-CyanophenolHCID 5360545Sodium

Product 1

HCID 13315035HCID 13315035, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

According to this reference, 1 mole of sodium salt of p-hydroxybenzo-nitrile and 1.7 moles of dibromodifluoromethane are dissolved in dimethylformamide, stirred at the room temperature for a day and distilled to obtain desired p-(bromodifluoromethoxy)-benzonitrile. However, the yield is only about 31.8%.

Workup

  1. distillationdistilled

Sources & evidence

ORD record
ord-fd20503cb35b4855bd83e92749ef7d5c
Source dataset
uspto-grants-1992_04
Patent number
US05105021

Reaction notes

Loading…