1-Amino-2-propanol → N-(2-hydroxypropyl)-2-[2-[7-methyl-5-[(6-methylsulfonyl-3-pyridinyl)oxy]-1H-indol-2-yl]-4,5-dihydro-1,3-thiazol-5-yl]acetamide
Reaction equation
[CH2:47]([N:48]=[C:49]=[N:50][CH2:51][CH2:52][CH2:53][N:54]([CH3:55])[CH3:56])[CH3:57].[CH3:1][c:2]1[cH:3][c:4]([O:20][c:21]2[cH:22][n:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]2)[cH:5][c:6]2[cH:7][c:8]([C:11]3=[N:15][CH2:14][CH:13]([CH2:16][C:17](=[O:18])[OH:19])[S:12]3)[nH:9][c:10]12.[CH3:58][N:59]([CH3:60])[CH:61]=[O:62].[ClH:46].[NH2:31][CH2:32][CH:33]([CH3:34])[OH:35].[OH2:63].[OH:36][n:37]1[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[n:44][n:45]1>>[CH3:1][c:2]1[cH:3][c:4]([O:20][c:21]2[cH:22][n:23][c:24]([S:27](=[O:28])(=[O:29])[CH3:30])[cH:25][cH:26]2)[cH:5][c:6]2[cH:7][c:8]([C:11]3=[N:15][CH2:14][CH:13]([CH2:16][C:17](=[O:19])[NH:31][CH2:32][CH:33]([CH3:34])[OH:35])[S:12]3)[nH:9][c:10]12Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-1a36eaafd6c24b98a4542e16499f1ae8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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