反应详情

温度

100 °C

1-Acetyl-4-(4-aminophenyloxy)piperidine (1.77 g) obtained in Example 1 was dissolved in dimethylformamide (10 ml) and to the mixture were added potassium carbonate (2.1 g), potassium iodide (0.2 g) and 2,2'-dichloroethyl ether (0.9 ml), followed by heating with stirring at 100° C. overnight. The mixture was worked up according to the same manner as that described in Example 1 to obtain a colorless oily compound (1.4 g).

1. temperatureby heating