huagongshe.com
HRID1086115

反应详情

EQUATION

反应方程式

HRID 1086115 的结构方程式

REACTANTS

反应物

5
结构：CCN1CCOCC1
HCID7525

N-Ethylmorpholine

C6H13NO

结构：C(=NC1CCCCC1)=NC1CCCCC1
HCID10868

Dicyclohexylcarbodiimide

C13H22N2

结构：On1nnc2ccccc21
HCID75771

1-Hydroxybenzotriazole

C6H5N3O

结构：O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1
HCID101987

Carbobenzoxyproline

C13H15NO4

结构：CC(C)[C@H](N)C(=O)OC(C)(C)C.Cl
HCID12490702

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)C(=O)OC(C)(C)C
HCID12286264

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

1.3 ml of N-ethylmorpholine and 2.2 g of DCC are added, at 0° C., to a solution of 2.49 g of Z-Pro-OH, 2.1 g of H-Val-OtBu.HCl and 1.35 g of HOBt in 20 ml of dimethylformamide. The subsequent procedure is as in Example 8a. The residue is triturated with petroleum ether, filtered off with suction and dried.

WORKUP

后处理

  1. customThe residue is triturated with petroleum ether
  2. filtrationfiltered off with suction
  3. customdried