6-Bromoquinoline → HCID 178422846, compound
Reaction equation
Brc1ccc2ncccc2c1.Cc1ccc2c(cnn2C2CCCCO2)c1[B-](F)(F)F.[K+]>CC#N.CC(=O)[O-].CC(=O)[O-].CC(C)(C)[O-].CCCCCC.CCc1cc(CC)cc(CC)c1.CCc1cccc(CC)c1.CN(C)C=O.Cc1ccccc1.O.[Li+].[Pd+2].c1ccc(P(c2ccccc2)c2ccccc2)cc1>Cc1ccc2c(cnn2C2CCCCO2)c1-c1ccc2ncccc2c1Participants
14
Reactant 2
Product 1
Reagents, catalysts & solvents 11
HCID 236647642-Propanol, 2-methyl-, lithium salt (1:1)Reagent
HCID 11776TriphenylphosphineCatalyst
HCID 167845palladium(II) acetateCatalyst
HCID 962WaterSolvent
HCID 1140TolueneSolvent
HCID 6228DimethylformamideSolvent
HCID 6342AcetonitrileSolvent
HCID 76021,3,5-TriethylbenzeneSolvent
HCID 8058HexaneSolvent
HCID 88641,3-DiethylbenzeneSolvent
HCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standardConditions
- Temperature
- 100 °C
Sources & evidence
- ORD record
- ord-48b0cbb8ed134159a2624b9ec23ca068
- Source dataset
- Rapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
- Original link
- View source
Reaction notes
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