HCID 63675640, compound → HCID 178422846, compound

HRID 1104949Notes

Reaction equation

HRID 1104949 reaction equation
Cc1ccc2c(cnn2C2CCCCO2)c1Br.F[B-](F)(F)c1ccc2ncccc2c1.[K+]>C1CCOC1.CC(=O)[O-].CC(=O)[O-].CC(C)(C)P(C(C)(C)C)C(C)(C)C.CC(C)(C)[O-].CCCCCC.CCc1cc(CC)cc(CC)c1.CCc1cccc(CC)c1.Cc1ccccc1.O.[Li+].[Pd+2]>Cc1ccc2c(cnn2C2CCCCO2)c1-c1ccc2ncccc2c1

Participants

13

Reactant 2

HCID 63675640HCID 63675640, compoundHCID 71307646HCID 71307646, compound

Product 1

HCID 178422846HCID 178422846, compoundYield 44.13%

Reagents, catalysts & solvents 10

HCID 236647642-Propanol, 2-methyl-, lithium salt (1:1)ReagentHCID 83681Tris(1,1-dimethylethyl)phosphineCatalystHCID 167845palladium(II) acetateCatalystHCID 962WaterSolvent2×HCID 1140TolueneSolventHCID 76021,3,5-TriethylbenzeneSolventHCID 8028TetrahydrofuranSolventHCID 8058HexaneSolventHCID 88641,3-DiethylbenzeneSolventHCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-10a9abaa257a4c89beda47c1f242aab1
Source dataset
Rapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
Original link
View source

Reaction notes

Loading…