Tetrahydrofuran → Ethyl 4-ethynylbenzoate

HRID 1114131Notes

Reaction equation

HRID 1114131 reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:13][Si:14]([CH3:15])([CH3:16])[C:17]#[CH:18].[CH3:20][CH2:21][CH2:22][CH2:23][N+:24]([CH2:25][CH2:26][CH2:27][CH3:28])([CH2:29][CH2:30][CH2:31][CH3:32])[CH2:33][CH2:34][CH2:35][CH3:36].[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[Cu:42][I:43].[F-:19].[I:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1>>[c:2]1([C:17]#[CH:18])[cH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1

Participants

8

Reactant 7

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 16028TetrabutylammoniumHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 66111TrimethylsilylacetyleneHCID 142891Ethyl 4-iodobenzoate

Product 1

HCID 15540683Ethyl 4-ethynylbenzoate

Sources & evidence

ORD record
ord-c7acafb086cc4ae1b7b7990aec5786e7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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