Dimethylformamide → N-[6-(3-{[3-(1-cyanocyclopropyl)benzoyl]amino}phenoxy)imidazo[1,2-b]pyridazin-2-yl]-6-fluoronicotinamide
Reaction equation
[CH3:48][N:49]([CH3:50])[CH:51]=[O:52].[CH3:53][N:54]([CH3:55])[C:56](=[O:57])[CH3:58].[Cl:42][C:43]([C:44]([Cl:45])=[O:46])=[O:47].[F:32][c:33]1[n:34][cH:35][c:36]([C:37](=[O:38])[OH:39])[cH:40][cH:41]1.[NH2:1][c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18]([c:19]4[cH:20][c:21]([C:25]5([C:28]#[N:29])[CH2:26][CH2:27]5)[cH:22][cH:23][cH:24]4)=[O:30])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:31]1.[O:59]1[CH2:60][CH2:61][CH2:62][CH2:63]1>>[NH:1]([c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18]([c:19]4[cH:20][c:21]([C:25]5([C:28]#[N:29])[CH2:26][CH2:27]5)[cH:22][cH:23][cH:24]4)=[O:30])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:31]1)[C:37]([c:36]1[cH:35][n:34][c:33]([F:32])[cH:41][cH:40]1)=[O:38]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5ab2bfee768b4e44ad47542680cc032c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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