Hydrochloric Acid → (E)-5-(3,4-dichlorostyryl)-2,3-dihydro-1-methyl-8-(2-thenyloxy)-1H-1,4-benzodiazepine
Reaction equation
[CH2:32]([P:33]([CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH3:44].[Cl:2][c:3]1[cH:4][c:5]([CH:6]=[CH:7][C:8]2=[N:9][CH2:10][CH2:11][N:12]([CH3:20])[c:13]3[c:14]2[cH:15][cH:16][c:17]([OH:19])[cH:18]3)[cH:21][cH:22][c:23]1[Cl:24].[ClH:1].[N:45]([C:46]([N:47]([CH3:48])[CH3:49])=[O:50])=[N:51][C:52]([N:53]([CH3:54])[CH3:55])=[O:56].[O:57]1[CH2:58][CH2:59][CH2:60][CH2:61]1.[s:25]1[c:26]([CH2:30][OH:31])[cH:27][cH:28][cH:29]1>>[Cl:2][c:3]1[cH:4][c:5]([CH:6]=[CH:7][C:8]2=[N:9][CH2:10][CH2:11][N:12]([CH3:20])[c:13]3[c:14]2[cH:15][cH:16][c:17]([O:19][CH2:30][c:26]2[s:25][cH:29][cH:28][cH:27]2)[cH:18]3)[cH:21][cH:22][c:23]1[Cl:24]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f7360848202f42f29f557efd3da4d0d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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