Hydrochloric Acid → 3-(3-bromo-2-(4-fluorophenyl)furo[2,3-b]pyridin-5-yl)-N-(1-phenylcyclopropyl)benzamide

HRID 1121055Notes

Reaction equation

HRID 1121055 reaction equation
[Br:45][c:46]1[c:47](-[c:64]2[cH:65][cH:66][c:67]([F:70])[cH:68][cH:69]2)[o:48][c:49]2[n:50][cH:51][c:52](-[c:55]3[cH:56][c:57]([C:58](=[O:59])[OH:60])[cH:61][cH:62][cH:63]3)[cH:53][c:54]12.[CH3:76][CH2:77][O:78][C:79]([CH3:80])=[O:81].[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[ClH:34].[O:71]=[CH:72][N:73]([CH3:74])[CH3:75].[P-:10]([F:11])([F:12])([F:13])([F:14])([F:15])[F:16].[c:35]1([C:41]2([NH2:44])[CH2:42][CH2:43]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1.[n:17]1([O:18][C:19]([N:20]([CH3:21])[CH3:22])=[N+:23]([CH3:24])[CH3:25])[c:26]2[n:27][cH:28][cH:29][cH:30][c:31]2[n:32][n:33]1>>[c:35]1([C:41]2([NH:44][C:58]([c:57]3[cH:56][c:55](-[c:52]4[cH:51][n:50][c:49]5[o:48][c:47](-[c:64]6[cH:65][cH:66][c:67]([F:70])[cH:68][cH:69]6)[c:46]([Br:45])[c:54]5[cH:53]4)[cH:63][cH:62][cH:61]3)=[O:59])[CH2:42][CH2:43]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 1945491-Phenyl-cyclopropylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 592336883-(3-Bromo-2-(4-fluorophenyl)furo[2,3-b]pyridin-5-yl)benzoic acid

Product 1

HCID 672180313-(3-bromo-2-(4-fluorophenyl)furo[2,3-b]pyridin-5-yl)-N-(1-phenylcyclopropyl)benzamide

Sources & evidence

ORD record
ord-fe6e8db429db44f4833a88150e022e40
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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