Acetaldehyde → 2,6-Difluoro-alpha-methyl-3-pyridinemethanol
Reaction equation
[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30].[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[CH:21]([CH3:22])=[O:23].[ClH:24].[F:13][c:14]1[n:15][c:16]([F:20])[cH:17][cH:18][cH:19]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[F:13][c:14]1[n:15][c:16]([F:20])[cH:17][cH:18][c:19]1[CH:21]([CH3:22])[OH:23]Participants
10
Sources & evidence
- ORD record
- ord-849b1a9451094ca88b85da05b4803d4a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…