Bromide ion → Ethyl 4-(4-methoxyphenyl)phenylacetate

HRID 1133579Notes

Reaction equation

HRID 1133579 reaction equation
[Br-:20].[Br:24][c:25]1[cH:26][cH:27][c:28](-[c:31]2[cH:32][cH:33][c:34]([O:37][CH3:38])[cH:35][cH:36]2)[cH:29][cH:30]1.[Br:39][CH2:40][C:41](=[O:42])[O:43][CH2:44][CH3:45].[CH2:21]([Mg+:22])[CH3:23].[CH3:52][O:53][CH2:54][O:55][CH3:56].[CH3:58][N:59]([CH3:60])[P:61](=[O:62])([N:63]([CH3:64])[CH3:65])[N:66]([CH3:67])[CH3:68].[ClH:46].[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1.[Zn:57].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[c:25]1([CH2:40][C:41](=[O:42])[O:43][CH2:44][CH3:45])[cH:26][cH:27][c:28](-[c:31]2[cH:32][cH:33][c:34]([O:37][CH3:38])[cH:35][cH:36]2)[cH:29][cH:30]1

Participants

11

Reactant 10

HCID 259Bromide ionHCID 313Hydrochloric AcidHCID 7748Ethyl bromoacetateHCID 8020DimethoxymethaneHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 12679HexamethylphosphoramideHCID 23994ZincHCID 40340054-Bromo-4'-methoxybiphenylHCID 178461628HCID 178461628, compound

Product 1

HCID 15733994Ethyl 4-(4-methoxyphenyl)phenylacetate

Sources & evidence

ORD record
ord-8d976a6a188b49cd947a794c96176ce4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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