Acetic Acid → tert-butyl N-[4-chloro-1-(3,5-difluorophenyl)-3-oxobutan-2-yl]carbamate
Reaction equation
[C:38]([O:39][CH3:40])([CH3:41])([CH3:42])[CH3:43].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][c:8]([F:13])[cH:9][c:10]([F:12])[cH:11]1)[NH:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22].[CH3:27][CH:28]([N-:29][CH:30]([CH3:31])[CH3:32])[CH3:33].[CH3:34][C:35](=[O:36])[OH:37].[I:23][CH2:24][Cl:25].[Li+:26].[OH2:44]>>[C:3]([CH:4]([CH2:5][c:6]1[cH:7][c:8]([F:13])[cH:9][c:10]([F:12])[cH:11]1)[NH:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])(=[O:22])[CH2:24][Cl:25]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-8652caa7c55540599670a01fd98b1d4f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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