Dimethylformamide → HCID 178453370, compound

HRID 1138376Notes

Reaction equation

HRID 1138376 reaction equation
[C:34]([CH3:35])([CH3:36])([CH3:37])[O:38][C:39]([NH:40][CH2:41][C:42]#[CH:43])=[O:44].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]([CH2:9][OH:10])[NH:11][c:12]1[c:13]2[n:14][cH:15][n:16]([CH:22]3[CH:23]([OH:33])[CH:24]([OH:32])[CH:25]([NH:27][C:28]([CH2:29][OH:30])=[O:31])[CH2:26]3)[c:17]2[n:18][c:19]([Cl:21])[n:20]1.[CH2:64]([NH:65][CH2:66][CH3:67])[CH3:68].[Cu:74][I:75].[O:69]=[CH:70][N:71]([CH3:72])[CH3:73].[Pd:76]([Cl:77])[Cl:78].[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1.[c:79]1([P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[cH:93][cH:94][cH:95][cH:96][cH:97]1.[c:98]1([P:99]([c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[cH:112][cH:113][cH:114][cH:115][cH:116]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]([CH2:9][OH:10])[NH:11][c:12]1[c:13]2[n:14][cH:15][n:16]([CH:22]3[CH:23]([OH:33])[CH:24]([OH:32])[CH:25]([NH:27][C:28]([CH2:29][OH:30])=[O:31])[CH2:26]3)[c:17]2[n:18][c:19]([C:43]#[C:42][CH2:41][NH:40][C:39]([O:38][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:44])[n:20]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8021DiethylamineHCID 11776Triphenylphosphine3×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 11073648tert-butyl N-(prop-2-yn-1-yl)carbamateHCID 90761245N-[4-[2-chloro-6-[(1-hydroxy-3-phenylpropan-2-yl)amino]purin-9-yl]-2,3-dihydroxycyclopentyl]-2-hydroxyacetamide

Product 1

HCID 178453370HCID 178453370, compound

Sources & evidence

ORD record
ord-8e59b861b38c4907a0321d1a793ebd3e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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