1,2-Dichloroethane → N-[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]benzamide

HRID 1142152Notes

Reaction equation

HRID 1142152 reaction equation
[CH2:1]([Cl:2])[CH2:3][Cl:4].[CH2:61]([Cl:62])[Cl:63].[CH3:55][CH2:56][O:57][C:58]([CH3:59])=[O:60].[CH:46]([N:47]([CH:48]([CH3:49])[CH3:50])[CH2:51][CH3:52])([CH3:53])[CH3:54].[NH2:24][CH2:25][C:26]1=[CH:27][C:28]([CH3:44])([CH3:45])[NH:29][c:30]2[cH:31][cH:32][c:33](-[c:36]3[c:37]([O:42][CH3:43])[cH:38][cH:39][cH:40][cH:41]3)[cH:34][c:35]21.[OH:15][C:16](=[O:17])[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[OH:5][n:6]1[c:7]2[c:8]([cH:9][cH:10][cH:11][cH:12]2)[n:13][n:14]1>>[C:16](=[O:17])([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[NH:24][CH2:25][C:26]1=[CH:27][C:28]([CH3:44])([CH3:45])[NH:29][c:30]2[cH:31][cH:32][c:33](-[c:36]3[c:37]([O:42][CH3:43])[cH:38][cH:39][cH:40][cH:41]3)[cH:34][c:35]21

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 243Benzoic AcidHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 22566510HCID 22566510, compound

Product 1

HCID 10408574N-[6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]benzamide

Sources & evidence

ORD record
ord-5404c0965fe74363b35c24d6c49d269b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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