Tetrahydrofuran → HCID 54712201, compound

HRID 1143565Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([OH:22])[c:7]([C:14](=[O:15])[NH:16][CH2:17][C:18](=[O:19])[O:20][CH3:21])[c:8](=[O:13])[n:9]([CH3:12])[c:10]2[cH:11]1.[C:23](#[CH:24])[Si:25]([CH3:26])([CH3:27])[CH3:28].[CH2:29]([N:30]([CH:31]([CH3:32])[CH3:33])[CH:34]([CH3:35])[CH3:36])[CH3:37].[Cu:43][I:44].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[c:2]1([C:24]#[C:23][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:3][cH:4][c:5]2[c:6]([OH:22])[c:7]([C:14](=[O:15])[NH:16][CH2:17][C:18](=[O:19])[O:20][CH3:21])[c:8](=[O:13])[n:9]([CH3:12])[c:10]2[cH:11]1

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 66111Trimethylsilylacetylene

HCID 81531Diisopropylethylamine

HCID 54681697Methyl 2-(7-bromo-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetate

Product 1

HCID 54712201HCID 54712201, compound

Sources & evidence

ORD record: ord-2301d72277a041edaf3c37cd86d651f3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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