Ammonium → 1-Benzyl-4-(2-benzyloxyphenyl)-4-piperidinol

HRID 1144395Notes

Reaction equation

HRID 1144395 reaction equation
[Br:17][CH2:18][CH2:19][Br:20].[CH2:22]([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[N:29]1[CH2:30][CH2:31][C:32](=[O:35])[CH2:33][CH2:34]1.[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([Br:16])[cH:12][cH:13][cH:14][cH:15]1.[Cl-:36].[I:21].[Mg:1].[NH4+:37].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([C:32]2([OH:35])[CH2:31][CH2:30][N:29]([CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:34][CH2:33]2)[cH:12][cH:13][cH:14][cH:15]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312ChlorideHCID 78391,2-DibromoethaneHCID 8028TetrahydrofuranHCID 192201-Benzyl-4-piperidoneHCID 24841Hydrogen iodideHCID 5618281-(Benzyloxy)-2-bromobenzeneHCID 5462224Magnesium

Product 1

HCID 118248891-Benzyl-4-(2-benzyloxyphenyl)-4-piperidinol

Sources & evidence

ORD record
ord-ce51f62a913c43fd8561eca9fbe658ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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