HRID1145634

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID962

Water

H2O

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID6344

Dichloromethane

CH2Cl2

HCID8471

Triethylamine

C6H15N

HCID65578

Ethanedioyl dichloride

C2Cl2O2

结构：NC(C(=O)c1ccc(=O)n(-c2c(F)cccc2F)c1)c1ccc(F)cc1F

HCID67253562

5-[2-Amino-2-(2,4-difluorophenyl)acetyl]-1-(2,6-difluorophenyl)pyridin-2-one

C19H12F4N2O2

HCID178431724

未命名化合物

PRODUCTS

生成物

结构：CC1(C)OC(=O)OC1C(=O)NC(C(=O)c1ccc(=O)n(-c2c(F)cccc2F)c1)c1ccc(F)cc1F

HCID178431725

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-50a8a488678f4921809103e06aa04735
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反应 SMILES

[CH3:1][C:2]1([CH3:11])[CH:3]([C:8](=[O:9])[Cl:10])[O:4][C:5](=[O:7])[O:6]1.[CH3:55][CH2:56][N:57]([CH2:58][CH3:59])[CH2:60][CH3:61].[Cl:12][C:13]([C:14]([Cl:15])=[O:16])=[O:17].[Cl:51][CH2:52][Cl:53].[ClH:23].[NH2:24][CH:25]([C:26](=[O:27])[c:28]1[cH:29][cH:30][c:31](=[O:42])[n:32](-[c:34]2[c:35]([F:41])[cH:36][cH:37][cH:38][c:39]2[F:40])[cH:33]1)[c:43]1[c:44]([F:50])[cH:45][c:46]([F:49])[cH:47][cH:48]1.[O:18]=[CH:19][N:20]([CH3:21])[CH3:22].[OH2:54]>>[CH3:1][C:2]1([CH3:11])[CH:3]([C:8](=[O:9])[NH:24][CH:25]([C:26](=[O:27])[c:28]2[cH:29][cH:30][c:31](=[O:42])[n:32](-[c:34]3[c:35]([F:41])[cH:36][cH:37][cH:38][c:39]3[F:40])[cH:33]2)[c:43]2[c:44]([F:50])[cH:45][c:46]([F:49])[cH:47][cH:48]2)[O:4][C:5](=[O:7])[O:6]1