Chloride → HCID 18982836, compound

HRID 1146547Notes

Reaction equation

HRID 1146547 reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[Cl-:37].[F:1][c:2]1[cH:3][c:4]([C:12]([CH:13]([CH3:14])[Cl:15])=[O:16])[cH:5][c:6]2[c:10]1[NH:9][C:8](=[O:11])[CH2:7]2.[Li+:38].[OH:17][C:18]1([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1>>[F:1][c:2]1[cH:3][c:4]([C:12]([CH:13]([CH3:14])[N:21]2[CH2:20][CH2:19][C:18]([OH:17])([c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[CH2:23][CH2:22]2)=[O:16])[cH:5][c:6]2[c:10]1[NH:9][C:8](=[O:11])[CH2:7]2

Participants

7

Reactant 6

HCID 312ChlorideHCID 6228DimethylformamideHCID 8471TriethylamineHCID 28486Lithium ionHCID 963874-Phenylpiperidin-4-olHCID 18982834HCID 18982834, compound

Product 1

HCID 18982836HCID 18982836, compound

Sources & evidence

ORD record
ord-72969f309f9a47ee89bfa514b45344d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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