Acetate → 1-(4-Fluorophenyl)piperazine

HRID 1146795Notes

Reaction equation

HRID 1146795 reaction equation
[Br:7][c:8]1[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]1.[C:23]([O-:24])(=[O:25])[CH3:26].[C:28]([O-:29])(=[O:30])[CH3:31].[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5][NH:6]1.[CH3:15][c:16]1[c:17]([CH3:18])[cH:19][cH:20][cH:21][cH:22]1.[Pd+2:27]>>[CH2:1]1[CH2:2][N:3]([c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[CH2:4][CH2:5][NH:6]1

Participants

6

Reactant 5

HCID 175Acetate2×HCID 4837PiperazineHCID 7237O-XyleneHCID 99931-Bromo-4-fluorobenzeneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 752601-(4-Fluorophenyl)piperazine

Sources & evidence

ORD record
ord-4e7108d879924cb38660fc3b21794359
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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