Nitrogen → N-(4-(1-(4-methoxybenzyl)-3-(3-(4-methylpiperazin-1-yl)prop-1-ynyl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Reaction equation
[CH2:142]1[O:143][CH2:144][CH2:145][CH2:146]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[n:9][c:10]([I:41])[c:11]3[c:12]2[n:13][cH:14][cH:15][c:16]3[O:17][c:18]2[c:19]([F:40])[cH:20][c:21]([N:24]([C:25](=[O:26])[C:27]3([C:30](=[O:31])[NH2:32])[CH2:28][CH2:29]3)[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[cH:22][cH:23]2)[cH:42][cH:43]1.[CH3:44][N:45]1[CH2:46][CH2:47][N:48]([CH2:51][C:52]#[CH:53])[CH2:49][CH2:50]1.[CH3:54][CH2:55][N:56]([CH2:57][CH3:58])[CH2:59][CH3:60].[Cu:63][I:64].[N:61]#[N:62].[cH:65]1[cH:66][cH:67][c:68]([P:69]([Pd:70]([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([P:90]([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[P:109]([c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)([c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)[c:122]2[cH:123][cH:124][cH:125][cH:126][cH:127]2)([c:128]2[cH:129][cH:130][cH:131][cH:132][cH:133]2)[c:134]2[cH:135][cH:136][cH:137][cH:138][cH:139]2)[cH:140][cH:141]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][n:8]2[n:9][c:10]([C:53]#[C:52][CH2:51][N:48]3[CH2:47][CH2:46][N:45]([CH3:44])[CH2:50][CH2:49]3)[c:11]3[c:12]2[n:13][cH:14][cH:15][c:16]3[O:17][c:18]2[c:19]([F:40])[cH:20][c:21]([N:24]([C:25](=[O:26])[C:27]3([C:30](=[O:31])[NH2:32])[CH2:28][CH2:29]3)[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[cH:22][cH:23]2)[cH:42][cH:43]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ada85cf342ec489799c81fa73288b85f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…