Potassium Cation → 1-Bromo-3-benzyloxy-4,5-difluorobenzene

HRID 1150382Notes

Reaction equation

HRID 1150382 reaction equation
[Br:17][CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1.[Br:1][c:2]1[cH:3][c:4]([F:10])[c:5]([F:9])[c:6]([OH:8])[cH:7]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][CH2:33][O:34][C:35]([CH3:36])=[O:37].[K+:11].[K+:12].[O-:13][C:14]([O-:15])=[O:16].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[OH2:38]>>[Br:1][c:2]1[cH:3][c:4]([F:10])[c:5]([F:9])[c:6]([O:8][CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:7]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 27733075-Bromo-2,3-Difluorophenol

Product 1

HCID 574706011-Bromo-3-benzyloxy-4,5-difluorobenzene

Sources & evidence

ORD record
ord-c91742542b45470e973b1df5164c1b0e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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